Alternative Activation of Human Macrophages Is Rescued by Estrogen Treatment In Vitro and Impaired by Menopausal Status | Zendy

Alice Toniolo | Zendy; Gian Paolo Fadini | Zendy; Serena Tedesco | Zendy; Roberta Cappellari | Zendy; Elisabetta Vegeto | Zendy; Adriana Maggi | Zendy; Angelo Avogaro | Zendy; Chiara Bolego | Zendy; Andrea Cignarella | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Alternative Activation of Human Macrophages Is Rescued by Estrogen Treatment In Vitro and Impaired by Menopausal Status

Author(s) -

Alice Toniolo,

Gian Paolo Fadini,

Serena Tedesco,

Roberta Cappellari,

Elisabetta Vegeto,

Adriana Maggi,

Angelo Avogaro,

Chiara Bolego,

Andrea Cignarella

Publication year - 2014

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2014-2751

Subject(s) - estrogen , endocrinology , medicine , cd163 , proinflammatory cytokine , estrogen receptor , cytokine , ex vivo , menopause , lipopolysaccharide , macrophage , in vivo , inflammation , biology , in vitro , biochemistry , microbiology and biotechnology , cancer , breast cancer

During their reproductive years, women are generally protected from cardiovascular disease events by their estrogen-replete status. Our starting hypothesis was that lower estrogen levels after menopause are associated with macrophage activation profiles skewed toward proinflammatory phenotypes. Research Design and Setting: This was an in vitro and ex vivo study in human blood-derived macrophages.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research