Positive Association Between Serum Levels of Bone Resorption Marker CTX and HbA1c in Women With Normal Glucose Tolerance
Author(s) -
Yan Xuan,
Lihao Sun,
Dongmei Liu,
Lin Zhao,
Bei Tao,
Weiqing Wang,
Hongyan Zhao,
Jianmin Liu,
Guang Ning
Publication year - 2014
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2014-2583
Subject(s) - medicine , endocrinology , bone resorption , osteocalcin , glucose homeostasis , glycated hemoglobin , resorption , bone remodeling , diabetes mellitus , impaired glucose tolerance , n terminal telopeptide , type 2 diabetes , insulin resistance , chemistry , alkaline phosphatase , biochemistry , enzyme
The bone formation marker osteocalcin (OCN) has a beneficial effect on glucose metabolism. In mice, the OCN bioactivity is induced by bone resorption. But in humans, the role of bone resorption in modulating glucose homeostasis is not clear.
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