Intact Pituitary Function is Decisive for the Catabolic Response to TNF-α: Studies of Protein, Glucose and Fatty Acid Metabolism in Hypopituitary and Healthy Subjects | Zendy

Ermina Bach | Zendy; Andreas Buch Møller | Zendy; Jens Otto Lunde Jørgensen | Zendy; Mikkel H. Vendelbo | Zendy; Niels Jessen | Zendy; Jes Olesen | Zendy; Steen B. Pedersen | Zendy; Thomas S. Nielsen | Zendy; Niels Møller | Zendy

Open Access

Intact Pituitary Function is Decisive for the Catabolic Response to TNF-α: Studies of Protein, Glucose and Fatty Acid Metabolism in Hypopituitary and Healthy Subjects

Author(s) -

Ermina Bach,

Andreas Buch Møller,

Jens Otto Lunde Jørgensen,

Mikkel H. Vendelbo,

Niels Jessen,

Jes Olesen,

Steen B. Pedersen,

Thomas S. Nielsen,

Niels Møller

Publication year - 2014

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2014-2489

Subject(s) - endocrinology , medicine , lipolysis , insulin , chemistry , insulin resistance , protein catabolism , carbohydrate metabolism , adipose tissue , biology , amino acid , biochemistry

TNF-α generates inflammatory responses and insulin resistance, lipolysis, and protein breakdown. It is unclear whether these changes depend on intact hypothalamo-pituitary stress hormone responses to trigger the release of cortisol and growth hormone.

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