Relationship Between Serum Sclerostin, Bone Metabolism Markers, and Bone Mineral Density in Maintenance Hemodialysis Patients | Zendy

Eiji Ishimura | Zendy; Senji Okuno | Zendy; Mitsuru Ichii | Zendy; Kyoko Norimine | Zendy; Tomoyuki Yamakawa | Zendy; Shigeichi Shoji | Zendy; Yoshiki Nishizawà | Zendy; Masaaki Inaba | Zendy

Open Access

Relationship Between Serum Sclerostin, Bone Metabolism Markers, and Bone Mineral Density in Maintenance Hemodialysis Patients

Author(s) -

Eiji Ishimura,

Senji Okuno,

Mitsuru Ichii,

Kyoko Norimine,

Tomoyuki Yamakawa,

Shigeichi Shoji,

Yoshiki Nishizawà,

Masaaki Inaba

Publication year - 2014

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2014-2372

Subject(s) - sclerostin , endocrinology , medicine , bone remodeling , bone mineral , bone resorption , n terminal telopeptide , hemodialysis , cancellous bone , chemistry , alkaline phosphatase , osteocalcin , osteoporosis , biochemistry , surgery , wnt signaling pathway , gene , enzyme

Sclerostin, which is secreted exclusively by osteocytes, is a negative regulator of bone formation. The role of sclerostin in chronic kidney disease-mineral and bone disorder is not well known. In the present study, we examined the relationship between serum sclerostin levels, bone turnover markers, and bone mineral density (BMD) of the radius in maintenance hemodialysis patients.

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