Interrelationships Between the Kinetics of VLDL Subspecies and HDL Catabolism in Abdominal Obesity: A Multicenter Tracer Kinetic Study
Author(s) -
Bruno Vergès,
Martin Adiels,
Jan Borén,
P. Hugh R. Barrett,
Gerald F. Watts,
Dick C. Chan,
Laurence Duvillard,
Sanni Söderlund,
Niina Matikainen,
Juhani Kahri,
Isabelle Robin,
MarjaRiitta Taskinen
Publication year - 2014
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2014-2365
Subject(s) - medicine , endocrinology , catabolism , very low density lipoprotein , apolipoprotein b , lipoprotein , biology , chemistry , cholesterol , metabolism
Low plasma high-density lipoprotein (HDL) cholesterol is a major abnormality in abdominal obesity. This relates due to accelerated HDL catabolism, but the underlying mechanism requires further elucidation. The relationships between HDL catabolism and other variables that may be modified in abdominal obesity, such as very low-density lipoprotein (VLDL) subspecies (VLDL1, VLDL2) kinetics, liver fat, or visceral adiposity, remain to be investigated.
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