Establishment and Characterization of Novel Human Primary and Metastatic Anaplastic Thyroid Cancer Cell Lines and Their Genomic Evolution Over a Year as a Primagraft | Zendy

Manoj Garg | Zendy; Ryoko Okamoto | Zendy; Yasunobu Nagata | Zendy; Deepika Kanojia | Zendy; Subhashree Venkatesan | Zendy; Maria Tito Anand | Zendy; Glenn D. Braunstein | Zendy; Jonathan W. Said | Zendy; Ngan Doan | Zendy; Quoc Ho | Zendy; Tadayuki Akagi | Zendy; Sigal Gery | Zendy; Lizhen Liu | Zendy; Kar Tong Tan | Zendy; Wee Joo Chng | Zendy; Henry Yang | Zendy; Seishi Ogawa | Zendy; H. Phillip Koeffler | Zendy

Open Access

Establishment and Characterization of Novel Human Primary and Metastatic Anaplastic Thyroid Cancer Cell Lines and Their Genomic Evolution Over a Year as a Primagraft

Author(s) -

Manoj Garg,

Ryoko Okamoto,

Yasunobu Nagata,

Deepika Kanojia,

Subhashree Venkatesan,

Maria Tito Anand,

Glenn D. Braunstein,

Jonathan W. Said,

Ngan Doan,

Quoc Ho,

Tadayuki Akagi,

Sigal Gery,

Lizhen Liu,

Kar Tong Tan,

Wee Joo Chng,

Henry Yang,

Seishi Ogawa,

H. Phillip Koeffler

Publication year - 2014

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2014-2359

Subject(s) - anaplastic thyroid cancer , context (archaeology) , primary tumor , cancer research , thyroid cancer , lymph node , oncology , metastasis , thyroid , cell culture , lymph node metastasis , cancer , medicine , biology , genetics , paleontology

Anaplastic thyroid cancer (ATC) has no effective treatment, resulting in a high rate of mortality. We established cell lines from a primary ATC and its lymph node metastasis, and investigated the molecular factors and genomic changes associated with tumor growth.

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