Obesity, Islet Cell Autoimmunity, and Cardiovascular Risk Factors in Youth at Onset of Type 1 Autoimmune Diabetes
Author(s) -
Maribel Cedillo,
Ingrid Libman,
Vincent C. Arena,
Lei Zhou,
Massimo Trucco,
Diego Ize-Ludlow,
Massimo Pietropaolo,
Dorothy Becker
Publication year - 2014
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2014-2340
Subject(s) - medicine , autoimmunity , overweight , type 1 diabetes , obesity , autoantibody , waist , diabetes mellitus , body mass index , cohort , type 2 diabetes , immunology , endocrinology , disease , antibody
The current increase in childhood type 1 diabetes (T1D) and obesity has led to two conflicting hypotheses and conflicting reports regarding the effects of overweight on initiation and spreading of islet cell autoimmunity vs earlier clinical manifestation of preexisting autoimmune β-cell damage driven by excess weight.
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