Modulation of Amino Acid Metabolic Signatures by Supplemented Isoenergetic Diets Differing in Protein and Cereal Fiber Content
Author(s) -
John Hattersley,
A. Pfeiffer,
Michael Roden,
KlausJürgen Petzke,
Daniela Hoffmann,
Natalia Rudovich,
Harpal S. Randeva,
Manu Vatish,
Martin Osterhoff,
Özlem Goegebakan,
Silke Hornemann,
P. Nowotny,
Jürgen Machann,
Johannes Hierholzer,
Christian von Loeffelholz,
Matthias Möhlig,
Ayman M. Arafat,
Martin O. Weickert
Publication year - 2014
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2014-2302
Subject(s) - overweight , medicine , type 2 diabetes , endocrinology , obesity , amino acid , chemistry , biology , food science , zoology , diabetes mellitus , biochemistry
Amino-acid (AA) metabolic signatures differ in insulin-resistant (IR) obese vs normal-weight subjects, improve after weight loss, and seem to predict the risk of type 2 diabetes. It is unknown whether weight-maintaining dietary measures aimed at influencing IR alter AA signatures of high-risk subjects.
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