Elevated Circulating Pigment Epithelium-Derived Factor Predicts the Progression of Diabetic Nephropathy in Patients With Type 2 Diabetes
Author(s) -
Elaine Hui,
ChunYip Yeung,
ChiHo Lee,
Yu Cho Woo,
Carol Ho-Yan Fong,
Wing-Sun Chow,
Aimin Xu,
Karen S.L. Lam
Publication year - 2014
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2014-2235
Subject(s) - pedf , medicine , microalbuminuria , diabetic nephropathy , albuminuria , type 2 diabetes , kidney disease , hazard ratio , renal function , diabetes mellitus , prospective cohort study , risk factor , endocrinology , confidence interval , gastroenterology , urology , angiogenesis
Pigment epithelium-derived factor (PEDF), a circulating glycoprotein with antiangiogenic, antioxidative, and anti-inflammatory properties, protects against diabetic nephropathy (DN) in animal models.
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