N-Acetylcysteine Administration Prevents Nonthyroidal Illness Syndrome in Patients With Acute Myocardial Infarction: A Randomized Clinical Trial | Zendy

Josi Vidart | Zendy; Simone Magagnin Wajner | Zendy; Rogério Sarmento Leite | Zendy; André Manica | Zendy; Beatriz D. Schaan | Zendy; P. Reed Larsen | Zendy; Ana Luiza Maia | Zendy

Open Access

N-Acetylcysteine Administration Prevents Nonthyroidal Illness Syndrome in Patients With Acute Myocardial Infarction: A Randomized Clinical Trial

Author(s) -

Josi Vidart,

Simone Magagnin Wajner,

Rogério Sarmento Leite,

André Manica,

Beatriz D. Schaan,

P. Reed Larsen,

Ana Luiza Maia

Publication year - 2014

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2014-2192

Subject(s) - medicine , myocardial infarction , placebo , acetylcysteine , hormone , randomized controlled trial , oxidative stress , thyroid , intensive care , gastroenterology , endocrinology , antioxidant , intensive care medicine , pathology , biochemistry , chemistry , alternative medicine

The acute phase of the nonthyroidal illness syndrome (NTIS) is characterized by low T3 and high rT3 levels, affecting up to 75% of critically ill patients. Oxidative stress has been implicated as a causative factor of the disturbed peripheral thyroid hormone metabolism.

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