Combination of Peptide YY3–36with GLP-17–36 amideCauses an Increase in First-Phase Insulin Secretion after IV Glucose
Author(s) -
Tricia Tan,
Victoria Salem,
R. Troke,
Ali Alsafi,
Benjamin Field,
Akila De Silva,
Shivani Misra,
Kevin Baynes,
Mandy Donaldson,
James Minnion,
Mohammad A. Ghatei,
Ian F. Godsland,
Stephen R. Bloom
Publication year - 2014
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2014-2143
Subject(s) - peptide yy , endocrinology , medicine , insulin , glucose homeostasis , glucagon like peptide 1 , pancreatic hormone , insulin resistance , chemistry , homeostasis , hormone , diabetes mellitus , amide , type 2 diabetes , neuropeptide , biochemistry , receptor , neuropeptide y receptor
The combination of peptide YY (PYY) and glucagon-like peptide-1 (GLP-1) has been proposed as a potential treatment for diabetes and obesity. However, the combined effects of these hormones, PYY(3-36) and GLP-1(7-36 amide), on glucose homeostasis are unknown.
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