Intra-Tissue Steroid Profiling Indicates Differential Progesterone and Testosterone Metabolism in the Endometrium and Endometriosis Lesions | Zendy

Kaisa Huhtinen | Zendy; Taija Saloniemi-Hein | Zendy; Pekka KeskiRahkonen | Zendy; Reena Desai | Zendy; Teemu D. Laajala | Zendy; Mia Ståhle | Zendy; Merja R. Häkkinen | Zendy; Michael Awosanya | Zendy; Pia Suvitie | Zendy; Harry Kujari | Zendy; Tero Aittokallio | Zendy; David J. Handelsman | Zendy; Seppo Auriola | Zendy; Antti Perheentupa | Zendy; Matti Poutanen | Zendy

Open Access

Intra-Tissue Steroid Profiling Indicates Differential Progesterone and Testosterone Metabolism in the Endometrium and Endometriosis Lesions

Author(s) -

Kaisa Huhtinen,

Taija Saloniemi-Hein,

Pekka KeskiRahkonen,

Reena Desai,

Teemu D. Laajala,

Mia Ståhle,

Merja R. Häkkinen,

Michael Awosanya,

Pia Suvitie,

Harry Kujari,

Tero Aittokallio,

David J. Handelsman,

Seppo Auriola,

Antti Perheentupa,

Matti Poutanen

Publication year - 2014

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2014-1913

Subject(s) - endometriosis , endometrium , endocrinology , medicine , menstrual cycle , progestin , hormone , testosterone (patch) , sex steroid , follicular phase , connective tissue , biology , steroid , pathology

Aberrant sex steroid signaling is suggested to promote endometriosis growth by several mechanisms, and the tissue concentrations of sex steroids are key determinants of the hormone action. However, their concentrations are only superficially known in the endometrium and endometriosis lesions.

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