11C-Methionine PET/CT Imaging of99mTc-MIBI-SPECT/CT-Negative Patients With Primary Hyperparathyroidism and Previous Neck Surgery | Zendy

Tatjana TraubWeidinger | Zendy; Marius E. Mayerhoefer | Zendy; Oskar Koperek | Zendy; Markus Mitterhauser | Zendy; Heying Duan | Zendy; Georgios Karanikas | Zendy; Bruno Niederle | Zendy; Martha Hoffmann | Zendy

Open Access

¹¹C-Methionine PET/CT Imaging of^99mTc-MIBI-SPECT/CT-Negative Patients With Primary Hyperparathyroidism and Previous Neck Surgery

Author(s) -

Tatjana TraubWeidinger,

Marius E. Mayerhoefer,

Oskar Koperek,

Markus Mitterhauser,

Heying Duan,

Georgios Karanikas,

Bruno Niederle,

Martha Hoffmann

Publication year - 2014

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2014-1267

Subject(s) - medicine , primary hyperparathyroidism , hyperparathyroidism , nuclear medicine , radiology , positron emission tomography , thyroid , thyroidectomy

(99m)Tc-Methoxy-isobutyl-isonitrile (MIBI) scintigraphy is a standard preoperative localization imaging modality in patients with primary hyperparathyroidism (pHPT). Its accuracy in localizing a hyperactive parathyroid gland after previous cervical surgery is limited. Recently, (11)C-methionine has been introduced as a promising radiotracer for pHPT imaging. Yet, few data exist for this technique in patients with persisting or recurrent pHPT before reoperation.

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