Open AccessPrimary Hyperparathyroidism in Young People. When Should We Perform Genetic Testing for Multiple Endocrine Neoplasia 1 (MEN-1)?
Author(s) -
Tina Harmer Lassen,
Lennart FriisHansen,
Åse Krogh Rasmussen,
Ulrich Knigge,
Ulla FeldtRasmussen
Publication year - 2014
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2013-4491
Subject(s) - primary hyperparathyroidism , multiple endocrine neoplasia , endocrine system , men1 , genetic testing , hyperparathyroidism , medicine , psychology , genetics , biology , hormone , gene
Multiple endocrine neoplasia (MEN-1) is a rare, autosomal dominant inherited disorder. Primary hyperparathyroidism (pHPT) is the most frequent and usually the earliest expression of MEN-1, with typical age of onset at 20-25 years. Early detection of the disease and correct treatment are therefore of great importance.
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