Open AccessBacterial DNA Translocation Holds Increased Insulin Resistance and Systemic Inflammatory Levels in Morbid Obese Patients
Author(s) -
Sergio Ortíz,
Pedro Zapater,
José Luis Estrada,
Pablo Enriquez,
Mónica del Rey,
Ángel Abad,
José M. Such,
Fèlix Lluı́s,
Rubén Francés
Publication year - 2014
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2013-4483
Subject(s) - proinflammatory cytokine , insulin resistance , medicine , gastroenterology , body mass index , sepsis , insulin , bacterial translocation , endocrinology , immunology , surgery , inflammation , chromosomal translocation , biology , gene , biochemistry
Morbidly obese patients show several common comorbidities associated with immunological alterations such as a sustained low-level proinflammatory profile. Bacterial product translocation is frequent in inflammation-related diseases and may aggravate patients' clinical outcome.
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