Continuous Subcutaneous Hydrocortisone Infusion versus Oral Hydrocortisone Replacement for Treatment of Addison's Disease: A Randomized Clinical Trial | Zendy

Marianne Øksnes | Zendy; Sigríður Björnsdóttir | Zendy; Magnus Isaksson | Zendy; Paal Methlie | Zendy; Siri Carlsen | Zendy; Roy M. Nilsen | Zendy; JanErik Broman | Zendy; Kai Triebner | Zendy; Olle Kämpe | Zendy; AnnaLena Hulting | Zendy; Sophie Bensing | Zendy; Eystein S. Husebye | Zendy; Kristian Løvås | Zendy

Open Access

Continuous Subcutaneous Hydrocortisone Infusion versus Oral Hydrocortisone Replacement for Treatment of Addison's Disease: A Randomized Clinical Trial

Author(s) -

Marianne Øksnes,

Sigríður Björnsdóttir,

Magnus Isaksson,

Paal Methlie,

Siri Carlsen,

Roy M. Nilsen,

JanErik Broman,

Kai Triebner,

Olle Kämpe,

AnnaLena Hulting,

Sophie Bensing,

Eystein S. Husebye,

Kristian Løvås

Publication year - 2014

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2013-4253

Subject(s) - medicine , hydrocortisone , glucocorticoid , circadian rhythm , morning , crossover study , endocrinology , randomized controlled trial , adrenal insufficiency , cushing's disease , disease , placebo , alternative medicine , pathology

Conventional glucocorticoid replacement therapy fails to mimic the physiological cortisol rhythm, which may have implications for morbidity and mortality in patients with Addison's disease.

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