Bone Mineral Density in Young Women With Primary Ovarian Insufficiency: Results of a Three-Year Randomized Controlled Trial of Physiological Transdermal Estradiol and Testosterone Replacement
Author(s) -
Vaishali Popat,
Karim A. Calis,
Sophia Kalantaridou,
Vien H. Vanderhoof,
Deloris E. Koziol,
James Troendle,
James C. Reynolds,
Lawrence M. Nelson
Publication year - 2014
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2013-4145
Subject(s) - testosterone (patch) , bone mineral , transdermal , randomized controlled trial , medicine , hormone replacement therapy (female to male) , bone density , physiology , endocrinology , gynecology , pharmacology , osteoporosis
Women with primary ovarian insufficiency have significantly lower serum estradiol and T levels compared with regularly menstruating women. They also have significantly reduced bone mineral density (BMD).
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