Sonic Hedgehog Signaling Is Active in Human Adrenal Cortex Development and Deregulated in Adrenocortical Tumors | Zendy

Débora Cristiane Gomes | Zendy; Letícia Ferro Leal | Zendy; Lívia M. Mermejo | Zendy; Carlos Alberto Scrideli | Zendy; Carlos Eduardo Martinelli | Zendy; Maria Candida Barisson Villares Fragoso | Zendy; Ana Claudia Latrônico | Zendy; Luíz Gonzaga Tone | Zendy; Sílvio Tucci | Zendy; José Andres Yunes | Zendy; Izilda Aparecida Cardinalli | Zendy; Maria José Mastellaro | Zendy; Sílvia Regina Brandalise | Zendy; Fernando Silva Ramalho | Zendy; Ayrton Custódio Moreira | Zendy; Leandra Naíra Zambelli Ramalho | Zendy; Margaret de Castro | Zendy; Sonir Roberto Rauber Antonini | Zendy

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Sonic Hedgehog Signaling Is Active in Human Adrenal Cortex Development and Deregulated in Adrenocortical Tumors

Author(s) -

Débora Cristiane Gomes,

Letícia Ferro Leal,

Lívia M. Mermejo,

Carlos Alberto Scrideli,

Carlos Eduardo Martinelli,

Maria Candida Barisson Villares Fragoso,

Ana Claudia Latrônico,

Luíz Gonzaga Tone,

Sílvio Tucci,

José Andres Yunes,

Izilda Aparecida Cardinalli,

Maria José Mastellaro,

Sílvia Regina Brandalise,

Fernando Silva Ramalho,

Ayrton Custódio Moreira,

Leandra Naíra Zambelli Ramalho,

Margaret de Castro,

Sonir Roberto Rauber Antonini

Publication year - 2014

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2013-4098

Subject(s) - cyclopamine , sonic hedgehog , gli1 , adrenal cortex , medicine , hedgehog signaling pathway , endocrinology , biology , ptch1 , gli3 , carcinogenesis , adrenocortical carcinoma , cancer research , signal transduction , gene expression , microbiology and biotechnology , cancer , gene , biochemistry , repressor

The sonic hedgehog (SHH) pathway plays a key role in rodent adrenal cortex development and is involved in tumorigenesis in several human tissues, but data in human adrenal glands are limited.

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