Open AccessFollicular Fluid Soluble Receptor for Advanced Glycation End-Products (sRAGE): A Potential Indicator of Ovarian Reserve
Author(s) -
Zaher Merhi,
Mohamad Irani,
Angela Doswell,
Jennifer Ambroggio
Publication year - 2013
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2013-3839
Subject(s) - follicular fluid , medicine , endocrinology , follicular phase , glycation , anti müllerian hormone , ovarian reserve , receptor , gonadotropin , rage (emotion) , ovary , body mass index , oocyte , andrology , hormone , biology , embryo , pregnancy , infertility , neuroscience , genetics , microbiology and biotechnology
The interaction of advanced glycation end-products (AGEs) with their cellular receptor (RAGE) is implicated in the pathogenesis of abnormal ovarian follicular growth. RAGE has a circulating secretory receptor form, soluble RAGE (sRAGE), which neutralizes the action of AGEs and might exert a protective role on the follicular environment.
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