Nuclear Factor κB–Dependent Regulation of Angiogenesis, and Metastasis in an In Vivo Model of Thyroid Cancer Is Associated With Secreted Interleukin-8
Author(s) -
Kevin T. Bauerle,
Rebecca E. Schweppe,
Gregory S. Lund,
Gregory Kotnis,
Gagan Deep,
Rajesh Agarwal,
Nikita Pozdeyev,
William M. Wood,
Bryan R. Haugen
Publication year - 2014
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2013-3636
Subject(s) - angiogenesis , thyroid cancer , cancer research , metastasis , cell growth , cancer , cytokine , biology , in vivo , anaplastic thyroid cancer , thyroid , tumor progression , cancer cell , cell culture , endocrinology , medicine , immunology , genetics , microbiology and biotechnology
Development of novel strategies in the treatment of advanced thyroid cancer are needed. Our laboratory has previously identified a role for nuclear factor κB (NF-κB) signaling in human thyroid cancer cell growth, survival, and invasion.
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