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Role of Salvage Targeted Therapy in Differentiated Thyroid Cancer Patients Who Failed First-Line Sorafenib
Author(s) -
Ramona Dadu,
Catherine Devine,
Mike Hernández,
Steven G. Waguespack,
Naifa L. Busaidy,
Mimi I. Hu,
Camilo Jiménez,
Mouhammed Amir Habra,
Rena V. Sellin,
Anita K. Ying,
Gilbert J. Cote,
Steven I. Sherman,
Maria E. Cabanillas
Publication year - 2014
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2013-3588
Subject(s) - sorafenib , medicine , salvage therapy , thyroid cancer , oncology , progressive disease , retrospective cohort study , surgery , cancer , gastroenterology , chemotherapy , hepatocellular carcinoma
Sorafenib, a tyrosine kinase inhibitor, is a common first-line therapy for advanced differentiated thyroid cancer (DTC). However, responses are not durable and drug toxicity remains a problem.

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