Hyperandrogenemia Predicts Metabolic Phenotype in Polycystic Ovary Syndrome: The Utility of Serum Androstenedione
Author(s) -
Michael OʼReilly,
Angela E. Taylor,
Nicola Crabtree,
Beverly Hughes,
Farfia Capper,
Rachel Crowley,
Paul M. Stewart,
Jeremy Tomlinson,
Wiebke Arlt
Publication year - 2014
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2013-3399
Subject(s) - androstenedione , polycystic ovary , phenotype , medicine , ovary , endocrinology , metabolic syndrome , biology , insulin resistance , genetics , obesity , androgen , hormone , gene
Polycystic ovary syndrome (PCOS) is a triad of anovulation, insulin resistance, and hyperandrogenism. Androgen excess may correlate with metabolic risk and PCOS consensus criteria define androgen excess on the basis of serum T. Here we studied the utility of the androgen precursor serum androstenedione (A) in conjunction with serum T for predicting metabolic dysfunction in PCOS.
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