Obestatin Levels Are Associated With C-Peptide and Antiinsulin Antibodies at the Onset, Whereas Unacylated and Acylated Ghrelin Levels Are Not Predictive of Long-Term Metabolic Control in Children With Type 1 Diabetes
Author(s) -
Flavia Prodam,
Francesco Cadario,
Simonetta Bellone,
Letizia Trovato,
Stefania Moia,
Erica Pozzi,
Silvia Savastio,
Gianni Bona
Publication year - 2014
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2013-3294
Subject(s) - medicine , ghrelin , endocrinology , obestatin , metabolic control analysis , type 2 diabetes , insulin , diabetes mellitus , body mass index , hormone
Ghrelin secretion is altered at the onset and after the start of insulin therapy in children with type 1 diabetes. Contemporary regulation of acylated ghrelin (AG), unacylated ghrelin (UAG), and obestatin (OBST) remains undefined in this disease. It is unknown as to whether they could be good predictors of changes in glucose and metabolic control.
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