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Transcriptome Profiling Reveals Differentially Expressed Transcripts Between the Human Adrenal Zona Fasciculata and Zona Reticularis
Author(s) -
Juilee Rege,
Yasuhiro Nakamura,
Tao Wang,
Todd Merchen,
Hironobu Sasano,
William E. Rainey
Publication year - 2013
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2013-3198
Subject(s) - biology , zona fasciculata , microbiology and biotechnology , microarray analysis techniques , microarray , gene expression profiling , zona reticularis , transcriptome , gene expression , gene , endocrinology , zona glomerulosa , adrenal gland , genetics , angiotensin ii , blood pressure
The human adrenal zona fasciculata (ZF) and zona reticularis (ZR) are responsible for the production of cortisol and 19-carbon steroids (often called adrenal androgens), respectively. However, the gene profiles and exact molecular mechanisms leading to the functional phenotype of the ZF and ZR are still not clearly defined. In the present study, we identified the transcripts that are differentially expressed in the ZF and ZR.

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