Cross-Ethnic Meta-Analysis of Genetic Variants for Polycystic Ovary Syndrome
Author(s) -
Yvonne V. Louwers,
Lisette Stolk,
André G. Uitterlinden,
Joop S.E. Laven
Publication year - 2013
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2013-2495
Subject(s) - polycystic ovary , ethnic group , genome wide association study , medicine , context (archaeology) , value (mathematics) , meta analysis , demography , gynecology , genetics , oncology , biology , single nucleotide polymorphism , genotype , gene , insulin resistance , obesity , sociology , anthropology , paleontology , machine learning , computer science
Genome-wide association studies (GWAS) have revealed new susceptibility loci for Chinese patients with polycystic ovary syndrome (PCOS). Because ethnic background adds to phenotypic diversities in PCOS, it seems plausible that genetic variants associated with PCOS act differently in various ethnic populations.
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