Open AccessIncreased Frequency of the Anti-Müllerian-Inhibiting Hormone Receptor 2 (AMHR2) 482 A>G Polymorphism in Women With Polycystic Ovary Syndrome: Relationship to Luteinizing Hormone Levels
Author(s) -
Neoklis A. Georgopoulos,
Eleni Karagiannidou,
Vasiliki Koika,
Nikolaos D. Roupas,
Anastasia Armeni,
Dimitra Marioli,
Efstathios Papadakis,
Corrine K. Welt,
Dimitrios Panidis
Publication year - 2013
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2013-2458
Subject(s) - endocrinology , medicine , anti müllerian hormone , polycystic ovary , biology , luteinizing hormone , hormone , prolactin , insulin , insulin resistance
The polycystic ovary syndrome (PCOS) is a common and complex disease without a clear pattern of inheritance. Anti-Müllerian hormone (AMH) has an inhibitory effect on FSH-stimulated follicle growth. Serum AMH levels are higher in women with PCOS than in normo-ovulatory women. The elevated AMH levels may reflect abnormalities in AMH signaling.
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