Lifecycle of Polycystic Ovary Syndrome (PCOS): From In Utero to Menopause | Zendy

Corrine K. Welt | Zendy; Enrico Carmina | Zendy

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Lifecycle of Polycystic Ovary Syndrome (PCOS): From In Utero to Menopause

Author(s) -

Corrine K. Welt,

Enrico Carmina

Publication year - 2013

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2013-2375

Subject(s) - anovulation , polycystic ovary , hyperandrogenism , context (archaeology) , menopause , gynecology , medicine , menstrual cycle , physiology , fertility , endocrinology , biology , obesity , hormone , insulin resistance , population , paleontology , environmental health

Polycystic ovary syndrome (PCOS) is diagnosed during the reproductive years when women present with 2 of 3 of the following criteria: 1) irregular menstrual cycles or anovulation, 2) hyperandrogenism, and 3) PCO morphology. However, there is evidence that PCOS can be identified from early infancy to puberty based on predisposing environmental influences. There is also increasing information about the PCOS phenotype after menopause. The goal of this review is to summarize current knowledge about the appearance of PCOS at different life stages and the influence of reproductive maturation and senescence on the PCOS phenotype.

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