Treatment of Neurohypophyseal Diabetes Insipidus
Author(s) -
Yutaka Oiso,
Gary L. Robertson,
Jens Peter Nørgaard,
Kristian Vinter Juul
Publication year - 2013
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2013-2326
Subject(s) - medicine , diabetes insipidus , desmopressin , polyuria , thirst , hyponatremia , fluid intake , vasopressin , antidiuretic , regimen , hypernatremia , ambulatory , fluid restriction , pediatrics , intensive care medicine , endocrinology , diabetes mellitus , sodium , chemistry , organic chemistry
In recent years, there have been several improvements in the treatment of neurohypophyseal diabetes insipidus (DI). They include new formulations of the vasopressin analog, desmopressin; a better understanding of the effect of fluid intake on dosing; and more information about treatments of infants, children, and pregnant women who present special challenges. This review aims to summarize past and current information relative to the safety and efficacy of treatments for the types of DI caused by a primary deficiency of vasopressin.
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