Targeted Next-Generation Sequencing Panel (ThyroSeq) for Detection of Mutations in Thyroid Cancer
Author(s) -
Mari. Nikiforova,
Abigail I. Wald,
Somak Roy,
Mary Beth Durso,
Yuri E. Nikiforov
Publication year - 2013
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2013-2292
Subject(s) - gnas complex locus , cancer research , thyroid cancer , thyroid carcinoma , cancer , dna sequencing , thyroid nodules , mutation , hras , biology , thyroid , medicine , kras , microbiology and biotechnology , pathology , genetics , gene
Next-generation sequencing (NGS) allows for high-throughput sequencing analysis of large regions of the human genome. We explored the use of targeted NGS for simultaneous testing for multiple mutations in thyroid cancer.
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