Association Between Vitamin D Metabolism Gene Polymorphisms and Risk of Islet Autoimmunity and Progression to Type 1 Diabetes: The Diabetes Autoimmunity Study in the Young (DAISY)
Author(s) -
Brittni N. Frederiksen,
Miranda Kroehl,
Tasha E. Fingerlin,
Randall Wong,
Andrea K. Steck,
Marian Rewers,
Jill M. Norris
Publication year - 2013
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2013-2256
Subject(s) - single nucleotide polymorphism , medicine , endocrinology , autoimmunity , hazard ratio , type 1 diabetes , vitamin d and neurology , diabetes mellitus , genotype , immunology , biology , confidence interval , genetics , gene , disease
Vitamin D metabolism genes have been associated with type 1 diabetes (T1D) risk; however, these genes have not been investigated for association with the preclinical phase of T1D, islet autoimmunity (IA). Studies of vitamin D metabolism genes may elucidate the role of vitamin D in complex diseases.
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