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Alemtuzumab-Related Thyroid Dysfunction in a Phase 2 Trial of Patients With Relapsing-Remitting Multiple Sclerosis
Author(s) -
Gilbert H. Daniels,
Anton Vladić,
Vesna Brinar,
И. А. Завалишин,
WILLIAM A. VALENTE,
Pedro Oyuela,
Jeffrey Palmer,
David Margolin
Publication year - 2013
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2013-2201
Subject(s) - medicine , alemtuzumab , thyroid , multiple sclerosis , euthyroid , interferon beta 1a , thyroid function , gastroenterology , anti thyroid autoantibodies , thyroid peroxidase , thyroiditis , population , pediatrics , immunology , antibody , autoantibody , transplantation , interferon beta , environmental health
Alemtuzumab, an anti-CD52 monoclonal antibody, increased the risk of thyroid dysfunction in CAMMS223, a phase 2 trial in relapsing-remitting multiple sclerosis.

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