Vitamin D Protects Human Endothelial Cells From Oxidative Stress Through the Autophagic and Survival Pathways
Author(s) -
Francesca Uberti,
D. Lattuada,
Vera Morsanuto,
Ugo Nava,
Giorgio Bolis,
Giovanni Vacca,
Diletta Francesca Squarzanti,
Carlo Cisari,
Claudio Molinari
Publication year - 2013
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2013-2103
Subject(s) - oxidative stress , autophagy , microbiology and biotechnology , apoptosis , reactive oxygen species , mitochondrial permeability transition pore , protein kinase b , mitochondrion , biology , viability assay , programmed cell death , signal transduction , endocrinology , chemistry , medicine , biochemistry
Recently, vitamin D (VitD) has been recognized as increasingly importance in many cellular functions of several tissues and organs other than bone. In particular, VitD showed important beneficial effects in the cardiovascular system. Although the relationship among VitD, endothelium, and cardiovascular disease is well established, little is known about the antioxidant effect of VitD.
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