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The exact mechanisms responsible for increased plasma triglyceride (TG) concentration in obese people are unclear, and it is not known whether excess energy intake per se is involved in the pathophysiology of this abnormality.

the journal of clinical endocrinology and metabolism/journal of clinical endocrinology and metabolism

One Day of Mixed Meal Overfeeding Reduces Hepatic Insulin Sensitivity and Increases VLDL Particle But Not VLDL-Triglyceride Secretion in Overweight and Obese Men