Comparative Effect of Zoledronic Acid Versus Denosumab on Serum Sclerostin and Dickkopf-1 Levels of Naive Postmenopausal Women With Low Bone Mass: A Randomized, Head-to-Head Clinical Trial
Author(s) -
Athanasios D. Anastasilakis,
Stergios A. Pοlyzos,
Athina Gkiomisi,
Ilias Bisbinas,
Spyridon Gerou,
Polyzois Makras
Publication year - 2013
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2013-1402
Subject(s) - sclerostin , zoledronic acid , n terminal telopeptide , medicine , endocrinology , osteoprotegerin , bone resorption , denosumab , bone remodeling , osteoporosis , osteocalcin , chemistry , activator (genetics) , receptor , alkaline phosphatase , wnt signaling pathway , biochemistry , gene , enzyme
Decreased bone formation due to a coupling effect limits bone mass increases after antiresorptive treatment.
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