Trabecular Bone Score (TBS)—A Novel Method to Evaluate Bone Microarchitectural Texture in Patients With Primary Hyperparathyroidism | Zendy

Barbara C. Silva | Zendy; Stéphanie Boutroy | Zendy; Chiyuan Zhang | Zendy; Donald J. McMahon | Zendy; Bin Zhou | Zendy; Ji Wang | Zendy; Julia Udesky | Zendy; Serge Cremers | Zendy; Marta Sarquis | Zendy; X. Edward Guo | Zendy; Didier Hans | Zendy; John P. Bilezikian | Zendy

Open Access

Trabecular Bone Score (TBS)—A Novel Method to Evaluate Bone Microarchitectural Texture in Patients With Primary Hyperparathyroidism

Author(s) -

Barbara C. Silva,

Stéphanie Boutroy,

Chiyuan Zhang,

Donald J. McMahon,

Bin Zhou,

Ji Wang,

Julia Udesky,

Serge Cremers,

Marta Sarquis,

X. Edward Guo,

Didier Hans,

John P. Bilezikian

Publication year - 2013

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2012-4255

Subject(s) - trabecular bone score , primary hyperparathyroidism , medicine , texture (cosmology) , dentistry , bone mineral , computer science , osteoporosis , artificial intelligence , image (mathematics) , quantitative computed tomography

In the milder form of primary hyperparathyroidism (PHPT), cancellous bone, represented by areal bone mineral density at the lumbar spine by dual-energy x-ray absorptiometry (DXA), is preserved. This finding is in contrast to high-resolution peripheral quantitative computed tomography (HRpQCT) results of abnormal trabecular microstructure and epidemiological evidence for increased overall fracture risk in PHPT. Because DXA does not directly measure trabecular bone and HRpQCT is not widely available, we used trabecular bone score (TBS), a novel gray-level textural analysis applied to spine DXA images, to estimate indirectly trabecular microarchitecture.

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