Open AccessValidation of a Novel Method for Determining the Renal Threshold for Glucose Excretion in Untreated and Canagliflozin-treated Subjects With Type 2 Diabetes Mellitus
Author(s) -
David Polidori,
Sue Sha,
Atalanta Ghosh,
Leona PlumMörschel,
Tim Heise,
Paul Rothenberg
Publication year - 2013
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2012-4205
Subject(s) - canagliflozin , excretion , endocrinology , medicine , type 2 diabetes mellitus , diabetes mellitus , renal physiology , glycosuria , renal function
The stepwise hyperglycemic clamp procedure (SHCP) is the gold standard for measuring the renal threshold for glucose excretion (RT(G)), but its use is limited to small studies in specialized laboratories.
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