Improving the Measurement of Serum Thyroglobulin With Mass Spectrometry | Zendy

Andrew N. Hoofnagle | Zendy; Mara Y. Roth | Zendy

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Improving the Measurement of Serum Thyroglobulin With Mass Spectrometry

Author(s) -

Andrew N. Hoofnagle,

Mara Y. Roth

Publication year - 2013

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2012-4172

Subject(s) - thyroglobulin , mass spectrometry , chromatography , chemistry , medicine , thyroid

Serum thyroglobulin (Tg) measurements are central to the management of patients treated for differentiated thyroid carcinoma. For decades, Tg measurements have relied on methods that are subject to interference by commonly found substances in human serum and plasma, such as Tg autoantibodies. As a result, many patients need additional imaging studies to rule out cancer persistence or recurrence that could be avoided with more sensitive and specific testing methods.

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