Elevated Endothelin-1 (ET-1) Levels May Contribute to Hypoadiponectinemia in Childhood Obesity | Zendy

Carmela Nacci | Zendy; Valentina Leo | Zendy; Leonarda De Benedictis | Zendy; Maria Rosaria Carratù | Zendy; Nicola Bartolomeo | Zendy; Maria Altomare | Zendy; Paola Giordano | Zendy; Maria Felicia Faienza | Zendy; Monica Montagnani | Zendy

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Elevated Endothelin-1 (ET-1) Levels May Contribute to Hypoadiponectinemia in Childhood Obesity

Author(s) -

Carmela Nacci,

Valentina Leo,

Leonarda De Benedictis,

Maria Rosaria Carratù,

Nicola Bartolomeo,

Maria Altomare,

Paola Giordano,

Maria Felicia Faienza,

Monica Montagnani

Publication year - 2013

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2012-4119

Subject(s) - medicine , endocrinology , endothelin 1 , adiponectin , vasodilation , endothelin receptor , receptor , von willebrand factor , obesity , chemistry , insulin resistance , platelet

Pediatric obesity is associated with endothelial dysfunction and hypoadiponectinemia, but the relationship between these two conditions remains to be fully clarified. Whether enhanced release of endothelin-1 (ET-1) may directly impair adiponectin (Ad) production in obese children is not known.

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