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Pharmacodynamics of Cinacalcet Over 48 Hours in Patients With Controlled Secondary Hyperparathyroidism: Useful Data in Clinical Practice
Author(s) -
María Dolores Arenas,
Vanesa de la Fuente,
Pablo Delgado,
María Teresa Gil,
Patrícia Gutiérrez,
Jorge Ribero,
Mariano Rodríguez,
Yolanda Almadén
Publication year - 2013
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2012-4003
Subject(s) - cinacalcet , pharmacodynamics , secondary hyperparathyroidism , medicine , clinical practice , hyperparathyroidism , pharmacology , urology , pharmacokinetics , calcium , parathyroid hormone , physical therapy
Cinacalcet induces immediate changes in serum PTH levels, but the pharmacodynamic effect throughout the daily dosing interval in controlled patients is unknown. Also, in patients with reduced PTH, it is unknown what happens in the first 24 hours after withdrawal.

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