Predominance of β-Cell Neogenesis Rather Than Replication in Humans With an Impaired Glucose Tolerance and Newly Diagnosed Diabetes
Author(s) -
S. Yoneda,
Sae Uno,
Hiromi Iwahashi,
Yukari Fujita,
A Yoshikawa,
Junji Kozawa,
Keisuke Okita,
Daisuke Takiuchi,
Hidetoshi Eguchi,
Hiroaki Nagano,
Akihisa Imagawa,
Iichiro Shimomura
Publication year - 2013
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2012-3832
Subject(s) - neogenesis , impaired glucose tolerance , medicine , endocrinology , diabetes mellitus , pdx1 , glucagon , insulin , somatostatin , type 2 diabetes , biology , islet
A decrease in pancreatic β-cell mass is involved in the development of type 2 diabetes.
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