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Weight Loss Induced by Roux-en-Y Gastric Bypass But Not Laparoscopic Adjustable Gastric Banding Increases Circulating Bile Acids
Author(s) -
Rohit Kohli,
David Bradley,
Kenneth D.R. Setchell,
J. Christopher Eagon,
Nada A. Abumrad,
Samuel Klein
Publication year - 2013
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2012-3736
Subject(s) - postprandial , medicine , endocrinology , weight loss , insulin , type 2 diabetes , glucose homeostasis , hormone , energy homeostasis , insulin resistance , diabetes mellitus , obesity
It has been hypothesized that increased plasma bile acids (BAs) contribute to metabolic improvements after Roux-en-Y gastric bypass (RYGB) surgery by the G protein-coupled receptor TGR5-mediated effects on glucagon-like peptide-1 secretion and thyroid hormones.

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