Impact of Switching From Zidovudine to Tenofovir Disoproxil Fumarate on Bone Mineral Density and Markers of Bone Metabolism in Virologically Suppressed HIV-1 Infected Patients; A Substudy of the PREPARE Study
Author(s) -
Aoife G. Cotter,
S.M.E. Vrouenraets,
Jennifer J. Brady,
Ferdinand W.N.M. Wit,
Christoph A. Fux,
Hansjakob Furrer,
Kees Brinkman,
Caroline Sabin,
Peter Reiss,
Patrick Mallon
Publication year - 2013
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2012-3686
Subject(s) - bone mineral , medicine , n terminal telopeptide , zidovudine , bone remodeling , emtricitabine , lamivudine , tenofovir , osteocalcin , endocrinology , urology , bone density , gastroenterology , human immunodeficiency virus (hiv) , viral load , osteoporosis , antiretroviral therapy , immunology , chemistry , virus , hepatitis b virus , biochemistry , alkaline phosphatase , viral disease , enzyme
In virologically suppressed, antiretroviral-treated patients, the effect of switching to tenofovir (TDF) on bone biomarkers compared to patients remaining on stable antiretroviral therapy is unknown.
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