Open AccessTranscription Factor KLLN Inhibits Tumor Growth byARSuppression, Induces Apoptosis byTP53/TP73Stimulation in Prostate Carcinomas, and Correlates With Cellular Differentiation
Author(s) -
Yu Wang,
Deepa Radhakrishnan,
Xin He,
Donna M. Peehl,
Charis Eng
Publication year - 2013
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2012-3490
Subject(s) - prostate cancer , androgen receptor , cancer research , prostate , stromal cell , carcinogenesis , pten , metastasis , transcription factor , biology , prostatectomy , medicine , apoptosis , cancer , gene , biochemistry , pi3k/akt/mtor pathway
KLLN is a newly identified gene with unknown function and shares a bidirectional promoter with PTEN.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom