Characterization of the Wnt Inhibitors Secreted Frizzled-Related Proteins (SFRPs) in Human Adipose Tissue | Zendy

Anna Ehrlund | Zendy; Niklas Mejhert | Zendy; Silvia LorenteCebrián | Zendy; Gaby Åström | Zendy; Ingrid Dahlman | Zendy; Jurga Laurencikiene | Zendy; Mikael Rydén | Zendy

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Characterization of the Wnt Inhibitors Secreted Frizzled-Related Proteins (SFRPs) in Human Adipose Tissue

Author(s) -

Anna Ehrlund,

Niklas Mejhert,

Silvia LorenteCebrián,

Gaby Åström,

Ingrid Dahlman,

Jurga Laurencikiene,

Mikael Rydén

Publication year - 2013

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2012-3416

Subject(s) - biology , adipose tissue , adipogenesis , adipokine , endocrinology , medicine , adiponectin , adipocyte , wnt signaling pathway , insulin resistance , white adipose tissue , microbiology and biotechnology , insulin , signal transduction

Wnt signaling regulates adipogenesis and adipocyte function. Secreted frizzled-related proteins (SFRPs) are a family of secreted proteins (SFRP1-5) that bind and inhibit Wnts. Several members, including SFRP5, have recently been implicated in adipocyte dysfunction in obesity.

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