Insulin-Like Growth Factor-I, Inflammatory Proteins, and Fibrosis in Subjects With Nonalcoholic Fatty Liver Disease
Author(s) -
Marta Letizia Hribal,
Teresa Procopio,
Salvatore Petta,
Angela Sciacqua,
Stefania Grimaudo,
Rosaria Maria Pipitone,
Francesco Perticone,
Giorgio Sesti
Publication year - 2013
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2012-3290
Subject(s) - nonalcoholic fatty liver disease , fibrosis , medicine , insulin , insulin resistance , growth factor , insulin like growth factor , inflammation , disease , endocrinology , fatty liver , gastroenterology , receptor
Inflammation may have a pathogenic role in the progression of nonalcoholic fatty liver disease (NAFLD); by contrast, the role of anti-inflammatory molecules has not been addressed. Low circulating levels of the anti-inflammatory molecule IGF-I have been described in subjects with NAFLD.
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