Mild Cold Exposure Modulates Fibroblast Growth Factor 21 (FGF21) Diurnal Rhythm in Humans: Relationship between FGF21 Levels, Lipolysis, and Cold-Induced Thermogenesis | Zendy

Paul Lee | Zendy; Robert J. Brychta | Zendy; Joyce D. Linderman | Zendy; Susan M. Smith | Zendy; Kong Y. Chen | Zendy; Francesco S. Celi | Zendy

Open Access

Mild Cold Exposure Modulates Fibroblast Growth Factor 21 (FGF21) Diurnal Rhythm in Humans: Relationship between FGF21 Levels, Lipolysis, and Cold-Induced Thermogenesis

Author(s) -

Paul Lee,

Robert J. Brychta,

Joyce D. Linderman,

Susan M. Smith,

Kong Y. Chen,

Francesco S. Celi

Publication year - 2012

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2012-3107

Subject(s) - fgf21 , lipolysis , thermogenesis , medicine , endocrinology , white adipose tissue , adipose tissue , area under the curve , chemistry , microdialysis , brown adipose tissue , biology , fibroblast growth factor , receptor , central nervous system

Cold exposure stimulates fibroblast growth factor 21 (FGF21) secretion in animals, enhancing the cold-induced thermogenesis (CIT) response through browning of white adipose tissue. In humans, the effects of cold exposure on circulating FGF21 levels are unknown.

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