Liquid Chromatography–Tandem Mass Spectrometry Analysis of Human Adrenal Vein 19-Carbon Steroids Before and After ACTH Stimulation | Zendy

Juilee Rege | Zendy; Yasuhiro Nakamura | Zendy; Fumitoshi Satoh | Zendy; Ryo Morimoto | Zendy; Michael R. Kennedy | Zendy; Lawrence C. Layman | Zendy; Seijiro Honma | Zendy; Hironobu Sasano | Zendy; William E. Rainey | Zendy

Open Access

Liquid Chromatography–Tandem Mass Spectrometry Analysis of Human Adrenal Vein 19-Carbon Steroids Before and After ACTH Stimulation

Author(s) -

Juilee Rege,

Yasuhiro Nakamura,

Fumitoshi Satoh,

Ryo Morimoto,

Michael R. Kennedy,

Lawrence C. Layman,

Seijiro Honma,

Hironobu Sasano,

William E. Rainey

Publication year - 2013

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2012-2912

Subject(s) - medicine , endocrinology , dehydroepiandrosterone , chemistry , estrone , androgen , testosterone (patch) , adrenocorticotropic hormone , androstenedione , adrenal gland , epitestosterone , acth receptor , adrenal adenoma , hormone , adenoma

A broad analysis of adrenal gland-derived 19-carbon (C19) steroids has not been reported. This is the first study that uses liquid chromatography-tandem mass spectrometry to quantify 9 C19 steroids (androgens and their precursors), estrone, and estradiol in the adrenal vein (AV) of women, before and after ACTH stimulation.

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