Reduction in the Risk of Clinical Fractures After a Single Dose of Zoledronic Acid 5 Milligrams
Author(s) -
Ian R. Reid,
Dennis M. Black,
Richard Eastell,
Christina BucciRechtweg,
Grace L. Su,
Trisha F. Hue,
Peter Mesenbrink,
Kenneth W. Lyles,
Steven Boonen
Publication year - 2013
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2012-2868
Subject(s) - zoledronic acid , reduction (mathematics) , medicine , mathematics , geometry
Annual infusions of zoledronic acid 5 mg over 3 years have been shown to reduce fracture incidence. There is now evidence that the effects of a single dose of zoledronic acid on bone mineral density and bone turnover last for much more than a year. Whether this is associated with sustained fracture prevention is not known.
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