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TheIRS1rs2943641 Variant and Risk of Future Cancer Among Morbidly Obese Individuals
Author(s) -
Cristina Maglio,
Ulrika Ericson,
Maria Antonella Burza,
Rosellina Margherita Mancina,
Carlo Pirazzi,
Johanna C. AnderssonAssarsson,
Kajsa Sjöholm,
Marco Giorgio Baroni,
PerArne Svensson,
Tiziana Montalcini,
Arturo Pujia,
Lars Sjöström,
Olov Wiklund,
Lena Carlsson,
Jan Borén,
Marju OrhoMelander,
Stefano Romeo
Publication year - 2013
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2012-2831
Subject(s) - medicine , hazard ratio , incidence (geometry) , cancer , insulin resistance , cohort , confidence interval , body mass index , obesity , cohort study , population , physics , environmental health , optics
Obesity and insulin resistance are risk factors for cancer development. The IRS1 rs2943641 genetic variant has been widely associated with insulin resistance.

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