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Bone Resorption Is Increased in Pheochromocytoma Patients and Normalizes following Adrenalectomy
Author(s) -
Annegreet G. VeldhuisVlug,
Mohammed El Mahdiui,
Erik Endert,
Annemieke C. Heijboer,
Eric Fliers,
Peter H. Bisschop
Publication year - 2012
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2012-2823
Subject(s) - bone remodeling , pheochromocytoma , liter , adrenalectomy , bone resorption , medicine , endocrinology , interquartile range
The sympathetic nervous system (SNS) controls bone turnover in rodents, but it is uncertain whether a similar role for the SNS exists in humans. Pheochromocytomas are catecholamine-producing neuroendocrine tumors. Because catecholamines are the neurotransmitters of the SNS, we hypothesized that pheochromocytoma patients have increased bone turnover.

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